Fight Colorectal Cancer

Hello world!

Posted by wpadmin on October 23rd, 2013

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Comments (1): Add a comment

Colorectal Cancer News in Brief: July 7

Posted by Kate's Blogs on July 7th, 2009

News in Brief catches up today after celebrating the Fourth of July with swimming, sailing, and time with family.  We hope you had as good a time relaxing as we did.

Research shows that children whose parents have cancer have more social and psychological problems, mice who are fed a high-fat Western-style diet don’t benefit from exercise and develop more colon polyps, and adding irinotecan to 5FU after surgery to remove liver mets adds no benefit but has more serious side effects.

The VA is upgrading equipment to sterilize endoscopes and train staff to clean them properly with $26 million from its reserve funds.  Two scientists at MIT are sampling and freezing their own stools each day to study changing patterns of millions of  microbes in the intestinal tract. Read the rest of this entry »

Phase III Sutent Trial for Colorectal Cancer Discontinued

Posted by Kate's Blogs on July 1st, 2009

Pfizer announced yesterday, June 30, 2009, that they are discontinuing a phase III trial comparing FOLFIRI chemotherapy alone to FOLFIRI with added Sutent® (sunitinib).

Based on results so far, the independent Data Monitoring Committee (DMC) determined that a significant reduction in progression-free survival was not statistically possible.  No new safety concerns were identified. Read the rest of this entry »

What is the Best Treatment in the Neoadjuvant Setting for Rectal Cancer?

Posted by Lenz on June 30th, 2009

At ASCO a number of studies showed the efficacy data of combining 5-FU or Xeloda with oxaliplatin in combination with radiation therapy in patients with rectal cancer. Read the rest of this entry »

Colorectal Cancer News in Brief: June 25

Posted by Kate's Blogs on June 27th, 2009

fawcettFarrah Fawcett died on Thursday, June 25, 2009 of anal cancer that had spread to her liver.  She was 62.  Anal cancer is much more rare than either colon or rectal cancer, affecting about 5,300 Americans in 2009. 710 will die from it.

In other headlines, the Caterpillar company works with Peoria hospitals and doctors to ensure quality colonoscopy for their employees and a Swiss laboratory will be the first to offer a blood screening test for colorectal cancer.

In research, MRI colonography is useful for patients who can’t have a full colonoscopy before surgery, screening colonoscopies are increasing for Medicare enrollees, and scientists have found factors in tumors that make nerves more sensitive to pain.

Read the rest of this entry »

Dr. Lenz: Genetic Signature Not Helpful to Predict Recurrence in Clinical Practice

Posted by Lenz on June 25th, 2009

At ASCO 2009 Dr. David Kerr from the United Kingdom presented data on a genetic signature which is associated with tumor recurrence in stage II colon cancer. However these data are not even close to being clinically meaningful.

These data have been discussed by Kate Murphy. However I wanted to follow up with the significance of the data. To increase the risk of recurrence from 12% to 22% is not in any way or form helpful in the clinic, particularly because this outcome is independent of treatment effect. Read the rest of this entry »

Poverty, Lack of Insurance Barriers to Reducing Colon Cancer

Posted by Kate's Blogs on June 25th, 2009

Although new diagnoses of colon and rectal cancer are decreasing in the United States, the benefit does not reach everyone.

No matter where they lived, incidence of colorectal cancer dropped significantly between 1995 and 2004 for white Americans aged 65 and over, most of whom have Medicare that covers colonoscopy screening.  However, colorectal cancer rates for whites from 50 to 64 did not fall if they lived in rural areas or counties where there was poverty, lack of insurance, or few primary care providers.

African Americans only benefited from reduced incidence if they were over 64 and living in an affluent community. Read the rest of this entry »

Hepatic Perfusion Treatment Improves Survival and Shrinks CRC Liver Tumors

Posted by Kate's Blogs on June 24th, 2009

Colorectal cancer patients whose cancer had spread to their livers benefited from surgery during which heated chemotherapy was pumped directly to their livers. Isolated hepatic perfusion (IHP) shrank tumors and increased survival time.  It may be a hopeful new approach to treating colorectal cancer that is widespread in the liver.

Median survival time after the treatment was a little over 17 months.  A third of patients lived two years or more.

A clinical trial of a similar hepatic perfusion technique without open surgery is currently available at the NIH Clinical Center in Bethesda, Maryland. Read the rest of this entry »

Colorectal Cancer News in Brief: June 19

Posted by Kate's Blogs on June 20th, 2009

In studies reported this week  fewer specialists managing colorectal cancer were found in US counties with large African American populations, older adults with cancer had significantly worse physical and mental health, and palliative sedation at the end of life did not hasten death.

In other headlines, colorectal cancer screening for the uninsured will begin on July 1 in Minnesota, and if screening reveals cancer, treatment will be covered under the Minnesota Medical Assistance program.  The FDA warned consumers not to use Zicam nasal gel or swabs to avoid loss of smell, and doctors advised patients on long-term Xeloda therapy to carry a letter from their oncologist explaining possible loss of fingerprints if they travel internationally. Read the rest of this entry »

Nestle's Refrigerator Cookie Dough Recalled: Risk of E.Coli

Posted by Kate's Blogs on June 19th, 2009

cookies2Throw out that refrigerated Nestles TOLL HOUSE Cookie Dough!  And don’t eat it raw or bake it.

The Food and Drug Administration has announced a voluntary recall of all varieties of Nestle® TOLL HOUSE® refrigerator cookie dough.  While no e. coli bacteria have been actually found in the dough, there have been a number of reports of consumers becoming ill after eating the raw dough.

Baking the cookies may not eliminate the risk of contamination because cooks may get bacteria on their hands or on other kitchen surfaces.

Nestle and the FDA emphasize that people should never eat raw cookie dough or other foods that are intended to be baked or cooked before eating.

The products involved in the voluntary recall include all varieties of Nestlé TOLL HOUSE refrigerated Cookie Bar Dough, Cookie Dough Tub; Cookie Dough Tube; Limited Edition Cookie Dough items; Seasonal Cookie Dough and Ultimates Cookie Bar Dough. A complete list is available from Nestle. It includes all varieties, not just chocolate chip.

Read the rest of this entry »